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Clinically Standardized 50% Trans-Resveratrol Formula

Reclaim Vibrant Cellular Youth & Energy With SelfPlus AGE+

A breakthrough cellular defense dietary supplement formulated with high-potency Japanese Knotweed extract (yielding 50% active Trans-Resveratrol). Engineered to activate SIRT1 longevity pathways, counteract cellular oxidative degradation, and restore peak metabolic vitality at the foundational cellular level.

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Sirtuin-1

Longevity Gene Activation

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Mitochondria

Deep ATP Energy Output

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Anti-Glycation

A.G.E. Protection

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1,840+ verified reviews

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SelfPlus AGE Plus Resveratrol Dietary Supplement Bottle with Japanese Knotweed and capsules
Standardized 250mg Japanese Knotweed (50% Trans-Resveratrol)
Unrivaled Cellular Quality

Why Choose SelfPlus AGE+ Over Generic Anti-Aging Supplements?

Most longevity supplements use unstandardized red wine extracts that contain less than 5% active trans-resveratrol. SelfPlus AGE+ provides high-bioavailability 50% Trans-Resveratrol extracted directly from Polygonum cuspidatum (Japanese Knotweed), delivering clinical-grade cellular rejuvenation.

Active Trans-Resveratrol Molecular Purity Extraction in SelfPlus AGE

Standardized 50% Trans-Isomer Purity

While cis-resveratrol is biologically inactive, SelfPlus AGE+ isolates the pure, bioactive trans-resveratrol isomer to cross the cellular membrane and activate youth genes.

Cellular Glycation and AGE Defense with Lemon Grass Extract

Targeted Anti-Glycation Shield

Advanced Glycation End-products (A.G.E.s) stiffen arteries and degrade skin collagen. SelfPlus AGE+ combines antioxidant polyphenols with lemon grass powder to combat cross-linking at its source.

Clean Vegan Cellulose Capsule Ingredients in SelfPlus AGE

Zero Fillers or Toxic Binders

Encapsulated inside 100% pure plant cellulose with magnesium stearate and white rice flour for smooth gut transit, optimal biological assimilation, and zero digestive distress.

Real Verified Results

What Real Verified Customers Say About SelfPlus AGE+

Read firsthand experiences from women and men across the United States who regained all-day stamina, radiant skin texture, and clear focus.

Verified customer Eleanor Vance holding SelfPlus AGE bottle
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"My Afternoon Brain Fog Is Completely Gone!"

"I was skeptical about another resveratrol pill, but SelfPlus AGE+ changed my mind within 3 weeks. I wake up before my alarm with clean energy, and my skin feels noticeably firmer and hydrated."

Eleanor Vance, 54

Austin, Texas β€’ Verified Buyer

Verified Order
Verified buyer Marcus Davis giving thumbs up with SelfPlus AGE supplement
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"Joint Flexibility & Workout Recovery Doubled"

"At age 61, stiff knees were keeping me off the pickleball court. Taking SelfPlus AGE+ daily gave me that bounce back. It's now an essential pillar of my morning wellness protocol."

Marcus Davis, 61

Denver, Colorado β€’ Verified Buyer

Verified Order
Verified customer Sarah Jenkins reviewing SelfPlus AGE 6 bottle supply
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"Best 6-Month Supply Investment I've Made"

"Ordered the 6-bottle bundle for the free shipping and bonuses. My lab work showed remarkable markers for metabolic flexibility and antioxidant capacity. Highly recommended!"

Sarah Jenkins, 48

Tampa, Florida β€’ Verified Buyer

Verified Order
Cellular Longevity Science

What Is SelfPlus AGE+?

SelfPlus AGE+ is a specialized, bioactive dietary formula engineered to address the root mechanisms of human biological senescence. While commercial anti-aging lotions only treat the dead stratum corneum layer of skin, SelfPlus AGE+ works from inside each living cell.

Its primary therapeutic driver is Polygonum cuspidatum (Japanese Knotweed) root, precisely standardized to deliver 50% pure Trans-Resveratrol (125mg pure active compound per capsule). Together with lemongrass powder and clean plant-derived stabilizers, it combats oxidative cell damage, reduces cellular senescence, and supports youthful cardiovascular, neural, and muscular function.

βœ“ Standardized to 50% Trans-Resveratrol (Active Isomer)
βœ“ Manufactured in an FDA-Registered & cGMP Certified Facility in the USA
βœ“ Non-GMO, Gluten-Free, Vegan Cellulose Capsules
Botanical Japanese Knotweed and scientific cellular model of SelfPlus AGE
Designed For Modern Living

Who Can Use SelfPlus AGE+?

SelfPlus AGE+ is formulated for adults over 30 who want to preserve their vitality, mental clarity, and mobility throughout the aging journey.

Active adults and seniors over 40 maintaining joint mobility with SelfPlus AGE

Adults 35 to 70+

Individuals noticing slower recovery, mid-day slumps, and declining metabolic flexibility.

Busy professionals boosting cognitive endurance and focus with antioxidants

High-Stress Professionals

Men and women exposed to chronic stress, poor sleep cycles, and high oxidative loads.

Fitness enthusiasts seeking faster muscular recovery and cellular endurance

Fitness Enthusiasts

Athletes looking to clear lactic acid faster and protect mitochondria from free radicals.

Skin and longevity conscious individuals fighting wrinkles and glycation

Skin & Longevity Seekers

Those aiming to defend their dermal matrix against advanced glycation and sunlight UV damage.

Cellular antioxidant protection and mitochondrial bioenergetics diagram
Cellular Mechanism

Why SelfPlus AGE+ Supports Antioxidant and Cellular Wellness

Every day, each cell in your body endures over 10,000 oxidative hits caused by metabolic byproducts, environmental pollution, blue light, and dietary toxins. Over time, these Reactive Oxygen Species (ROS) impair mitochondrial membranes, leading to energy depletion and early cell death.

SelfPlus AGE+ acts as an internal biological buffer:

  • β€’ Stimulates Endogenous Superoxide Dismutase (SOD): Rather than just providing passive antioxidants, trans-resveratrol activates your body's master antioxidant enzymes.
  • β€’ Protects Telomere Integrity: Promotes cellular repair factors that safeguard chromosomal end-caps from accelerated degradation.
  • β€’ Inhibits NF-kB Inflammatory Triggers: Modulates silent, smoldering micro-inflammation that exhausts tissues over the years.
Synergistic Health

What SelfPlus AGE+ Is Designed to Complement

SelfPlus AGE+ is not a magic fix for poor habits. It is engineered to seamlessly amplify your existing foundational longevity practices.

Intermittent fasting and caloric restriction protocol supported by SelfPlus AGE

Intermittent Fasting & Autophagy

Trans-resveratrol acts as a caloric restriction mimetic, triggering cellular debris cleanup (autophagy) without requiring starvation.

Mediterranean polyphenol-rich diet paired with SelfPlus AGE supplement

Polyphenol-Rich Nutrition

Boosts the cellular absorption of dietary polyphenols from extra virgin olive oil, wild berries, leafy greens, and green tea.

Zone 2 aerobic exercise and cardiovascular training supported by resveratrol

Zone-2 & Resistance Training

Accelerates mitochondrial biogenesis triggered by exercise, helping muscles recover stronger and experience less soreness.

3-Stage Biological Cascade

How Does SelfPlus AGE+ Work Inside Your Body?

From your very first dose, SelfPlus AGE+ initiates a synchronized cellular restoration protocol.

1
Trans-resveratrol cellular uptake and bioavailability step

Rapid Absorption

The standardized trans-isomer bypasses intestinal breakdown, entering circulation to deliver active polyphenols directly to vascular and neural tissues.

2
Sirtuin gene activation and NAD dependent longevity pathways

SIRT1 Gene Activation

Resveratrol binds to the allosteric site of Sirtuin-1 enzymes, signaling DNA repair machinery and boosting clean mitochondrial ATP generation.

3
Collagen structural defense and cellular matrix resilience against AGEs

Collagen & Dermal Protection

Lemon grass bioflavonoids inhibit sugar molecules from bonding to collagen fibers, defending dermal bounce, arterial flexibility, and joint comfort.

Head-to-Head Comparison

SelfPlus AGE+ Compared With Other Aging Wellness Approaches

See how high-purity Japanese Knotweed trans-resveratrol measures up against ordinary market alternatives.

Feature & Mechanism SelfPlus AGE+ Generic Red Wine Extracts Standard Multivitamins Synthetic Anti-Aging Pills
Standardized Trans-Resveratrol βœ… 50% Standardized ❌ Under 5% Cis-form ❌ 0% (None) ⚠️ Synthetic / Weak
Direct Sirtuin-1 (SIRT1) Activation βœ… Proven Mechanism ❌ Negligible ❌ None ⚠️ Unstable
Advanced Glycation (A.G.E.) Defense βœ… Dual Botanical Action ❌ No Glycation Shield ❌ No ❌ No
Digestive Bioavailability βœ… Micronized Root Extract ⚠️ Destroyed by Stomach Acid Moderate ❌ Poor GI Absorption
Safety, Fillers & Stimulants βœ… 100% Vegan, Zero Caffeine ⚠️ Often contains sulfites Standard fillers ❌ Unregulated synthetics
60-Day Money-Back Guarantee βœ… 100% Full Refund Guarantee ❌ No Guarantee ❌ Store Credit Only ❌ Strict Restocking Fees
Transformational Wellness

Comprehensive Whole-Body Benefits

Targeting senescence at the root unlocks sustained improvements throughout multiple biological systems.

Clean non-jittery cellular energy and stamina boost from SelfPlus AGE

Non-Jittery Cellular Stamina

Boosts mitochondrial ATP synthesis so you power through your workday without caffeine crashes.

Skin collagen elasticity and deep dermal hydration improvement

Dermal Elasticity & Firmness

Protects collagen fibers against sugar-induced cross-linking, smoothing fine lines and restoring skin suppleness.

Cardiovascular arterial health and nitric oxide endothelial support

Vascular & Arterial Flexibility

Enhances endothelial nitric oxide release, encouraging healthy blood pressure and effortless microcirculation.

Cognitive clarity neuroprotection and mental focus from resveratrol

Sharp Neural Focus

Crosses the blood-brain barrier to shield vulnerable neurons against oxidative stress, banishing morning brain fog.

Self-Assessment Checklist

Is SelfPlus AGE+ a Good Fit for Your Wellness Routine?

If you check 2 or more of the following conditions, your cellular machinery is likely facing high oxidative load and glycation stress:

1 You experience a persistent 2:00 PM energy slump despite 7+ hours of sleep.
2 You notice slower recovery in your muscles and joints following light exercise.
3 Your skin shows loss of bounce, dehydration, or deeper lines from sun exposure.
4 You are proactively investing in long-term cardiovascular and metabolic wellness.
Active healthy morning wellness routine with a glass of water and SelfPlus AGE
100% Transparent Label

SelfPlus AGE+ Ingredients Breakdown

Every single ingredient inside SelfPlus AGE+ is disclosed with zero proprietary blends, artificial preservatives, or chemical coloring agents.

Japanese Knotweed root extract standardized to 50% trans-resveratrol
Active Hero β€’ 250mg

Japanese Knotweed Root

Standardized to contain 50% Trans-Resveratrol (125mg active yield). Crosses cellular membranes to activate SIRT1 genes and promote mitochondrial renewal.

Herbal pure lemon grass powder for cellular anti-glycation defense
Bioflavonoid Complex

Lemon Grass Powder

Rich in citral and luteolin bioflavonoids. Synergistically binds free sugars in the bloodstream, neutralizing cross-linking glycation reactions.

Natural white rice flour flow agent and plant cellulose capsule
Natural Flow Agent

White Rice Flour

Replaces synthetic silicon dioxide and talc fillers. Ensures stable encapsulation and uniform dispersion inside the capsule.

Hypoallergenic vegetable cellulose vegetarian capsule
Clean Delivery

Plant Cellulose Capsule

100% vegetarian capsule that dissolves smoothly in the stomach without causing nausea, bloating, or gelatin-associated allergies.

Supplement Facts

Serving Size: 1 Capsule β€’ Servings Per Container: 30

Amount Per Serving % Daily Value
Japanese Knotweed (root)
(Containing 50% Trans-Resveratrol) (Polygonum cuspidatum)
250 mg   †
Magnesium Stearate, Lemon Grass Powder, White Rice Flour †

† Daily Value not established. Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients: Vegetable Capsule (Cellulose), Cellulose.

Effortless Daily Protocol

How To Use SelfPlus AGE+ for Maximum Results

Achieving long-term cellular rejuvenation requires consistency and optimal absorption timing.

1
Taking 1 capsule of SelfPlus AGE in the morning with a glass of water

Take 1 Capsule Daily

Consume 1 veggie capsule each morning with a full 8 oz glass of water to hydrate cells upon waking.

2
Pairing trans-resveratrol supplement with healthy dietary fats like avocado or yogurt

Pair With Healthy Fats

Resveratrol is lipophilic (fat-soluble). Taking it with avocado, eggs, or olive oil boosts absorption up to 3.5x.

3
Consistent 90 day daily longevity routine calendar tracker

Maintain for 90–180 Days

Cellular turnover takes time. Sustained daily use allows mitochondrial density and collagen matrices to regenerate fully.

Peer-Reviewed Research

The Science Behind SelfPlus AGE+

Groundbreaking studies in modern molecular biology have identified Sirtuins as master regulatory proteins controlling DNA repair, mitochondrial biogenesis, and cellular longevity. However, without molecular co-activators, sirtuin activity drops by as much as 60% after age 40.

Clinical literature published by Harvard medical researchers confirmed that pure trans-resveratrol serves as a potent STAC (Sirtuin-Activating Compound). By directly binding to SIRT1, it mimics the beneficial metabolic effects of severe caloric restriction, signaling cells to prioritize repair, autophagy, and mitochondrial integrity.

"Trans-resveratrol demonstrates significant capacity to modulate longevity pathways, inhibit oxidative stress cascades, and protect structural collagen from Advanced Glycation End-products."

Scientific sirtuin gene research and molecular longevity diagram
100% 60-Day Money Back Guarantee Official Gold Seal
Zero-Risk Investment

100% Risk-Free 60-Day Money-Back Guarantee

We understand that trying a new dietary supplement requires confidence. That is why your order today is protected by a ironclad 60-day, 100% money-back guarantee.

Try SelfPlus AGE+ for two full months. Experience the surging morning energy, sharper mental focus, and smoother skin texture. If for any reason you are not completely thrilled with your physical results, simply contact customer support and return the bottles (even if they are empty!) for a prompt, 100% refundβ€”no questions asked.

βœ“ 100% Refund Promptly Processed β€’ βœ“ Empty Bottle Returns Accepted
Order 3 or 6 Bottles Today

Get 2 Exclusive Free Longevity Bonuses (Value $108)

When you select a multi-bottle bundle today, you gain immediate digital access to two bestselling longevity guides.

Bonus eBook: The 21-Day Cellular Detox Protocol
BONUS #1 (Retail $55)

The 21-Day Cellular Detox Protocol

Step-by-step nutritional blueprint revealing the exact grocery items, teas, and breathing exercises that clear senescent "zombie" cells out of tissues.

Free Instant Download With 3 & 6 Bottles

Bonus eBook: Ageless Skin Secrets & Glycation Shields
BONUS #2 (Retail $53)

Ageless Skin: The Anti-Glycation Kitchen

Learn simple culinary marinades, spice combinations, and bedtime tonics that prevent sugar molecules from degrading skin collagen fibers.

Free Instant Download With 3 & 6 Bottles

Balanced Assessment

Pros and Cons of SelfPlus AGE+

An objective review of the advantages and limitations you should know before ordering.

βœ“ The Pros

  • βœ“ Standardized 50% Trans-Resveratrol provides potent biological activity.
  • βœ“ Dual cellular action: Activates SIRT1 and shields collagen from glycation.
  • βœ“ Convenient single daily veggie capsule; 100% vegan and gluten-free.
  • βœ“ Produced under strict cGMP standards in FDA-registered USA facilities.
  • βœ“ Risk-free 60-day money-back guarantee with empty bottle protection.

βœ• The Cons

  • βœ• Only available through the official online portal to avoid counterfeit stock.
  • βœ• Requires consistency: peak cellular benefits manifest over 60–90 days.
  • βœ• High demand frequently causes stock shortages on the 6-bottle bundle.
Direct-From-Manufacturer Pricing

Claim Your Discounted Bottles of SelfPlus AGE+

Choose the 180-day or 90-day supply to unlock maximum savings, free shipping, and two digital longevity books.

1 Bottle

30-Day Starter Supply

Single bottle starter supply of SelfPlus AGE
$69 / bottle

Standard Price: $99

βœ“ 30-Day Cellular Reset

βœ“ 60-Day Money-Back Guarantee

βœ— Small Shipping Fee Applies

ORDER 1 BOTTLE NOW
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6 Bottles

180-Day Ultimate Longevity Supply

6 bottle best value 180 day supply bundle of SelfPlus AGE
$49 / bottle

TOTAL: $294 (Save $300 Retail!)

βœ“ 2 FREE Longevity E-Books Included

βœ“ FREE USA Shipping Included

βœ“ Maximum Sirtuin Pathway Saturation

βœ“ 60-Day 100% Money-Back Guarantee

CLAIM 6 BOTTLES DISCOUNT →

3 Bottles

90-Day Cellular Renewal Supply

3 bottle 90 day supply package of SelfPlus AGE
$59 / bottle

TOTAL: $177 (Save $120)

βœ“ 2 FREE Longevity E-Books Included

βœ“ FREE USA Shipping Included

βœ“ 60-Day Money-Back Guarantee

ORDER 3 BOTTLES NOW
Got Questions?

Frequently Asked Questions Of SelfPlus AGE+

Find instant answers regarding dosage, compatibility, shipping, and guarantees.

How does SelfPlus AGE+ differ from drinking red wine? +

A standard glass of red wine contains less than 1–2 mg of unstable resveratrol, along with alcohol and sulfites that strain liver enzymes. To achieve the 125mg pure active Trans-Resveratrol in one capsule of SelfPlus AGE+, you would need to consume over 70 bottles of red wine daily. SelfPlus AGE+ delivers the pure compound without alcohol or calories.

Are there any negative side effects? +

SelfPlus AGE+ is made with 100% natural, vegetarian ingredients and is free of common allergens, gluten, dairy, and artificial stimulants. It has demonstrated an exceptional safety profile. If you have an existing medical condition or are taking prescription blood thinners, consult your healthcare provider before beginning any new regimen.

How long does delivery take inside the United States? +

Orders are dispatched via USPS Priority or FedEx within 24 hours of confirmation. Delivery across the continental United States typically takes between 3 to 5 business days. International deliveries arrive in 8 to 14 business days depending on customs.

Is this a one-time payment or a recurring subscription? +

Your order today is a strict one-time single payment. There are no automatic monthly billings, hidden subscriptions, or recurrent charges. If you wish to reorder later, you can place a new order on this page.

Official Direct Verification

Discounted SelfPlus AGE+ Available For A Limited Window

Due to strict quality testing and seasonal harvests of high-potency Japanese Knotweed root, batch inventory is capped. Secure your 180-day or 90-day supply today to lock in manufacturer discounts before stock is reserved.

Transparent Checkout Flow

What Happens After I Click The β€œBuy Now” Button?

Here is the exact step-by-step experience you will see once you select your package:

1

256-Bit Encrypted Checkout

You are directed to the official 256-bit SSL encrypted secure payment terminal where your payment data is strictly protected.

2

Instant Order Receipt & Bonus Access

You receive an instant email receipt containing your order summary and immediate digital download access to both longevity books.

3

Discrete Rapid Shipping

Our FDA-registered fulfillment center packages your fresh bottles in a clean, plain box and emails you a live tracking link within 24 hours.

SelfPlus AGE supplement final discount order bottle

Order Your Discounted Bottle Of SelfPlus AGE+ Now

Reclaim your cellular energy, protect collagen from damaging glycation, and support everyday vitality with pure standardized Trans-Resveratrol.

Backed by our 60-day 100% money-back guarantee β€’ No recurring subscriptions β€’ 100% secure payment